Chemical Engineer - Chromatography (0-1 yrs)
Job Responsibility :
- Actively involved in feasibility, process optimisation and laboratory scale up, cost reduction, prepartion and isolation of impurities, purification by recrystallisation, salt formation, fractional distillation, high vacuum distillation and column chromatography.
- Scaling up and technology transfer to plant for production.
- Result interpretation of GC, HPLC, NMR, IR & other routine analytical analysis.
- Name reactions handled such as a Suzuki coupling, buchwald harrowing reaction. Witting reaction, Acid Amine coupling reaction performed such as protection - De protection, bromination, Chlorination, Swern Oxidation, Stille reaction, Nitration etc.
- Having good knowledge of Chemisty.
- Good knowledge and hands of expirence of chemicals, solvents, instruments as well as glass ware to be used in chemical industries.
- Able to explain coupling reactions, catalytic Hadrogenation, oxidation, protection of groups and condensation reactions.
- Knowledge about reaction mechanisms, chemical properties, safe handling of chemicals and their deprotections.
- Experienced in Hazardous chemicals and their handling, precautions, risk factor, safety as well as decomposition of chemicals.
- Working experience on micro scale as well as large scale projects.
- Manage, maintain records and co-ordinate for all R&D activities.
- Exhibit innovative approach to achieving project activities by taking inputs from team members and following the instructions.
- Maintain accurate records of all work carried out and suggest patent protection as required.
- Should perform experiments meticulously
- Conduct experiments as planned and ensure gathering proper data on custom synthesis, analytical developments, impurity profile etc.
- To ensure that a quality system is established implemented and maintained in accordance with the ISO 9001 quality management system standards.
- To ensure that information security management system is established, implemented and maintained in accordance with the ISO 27001 standards.
- To follow all ISMS policy.
- Review and develops reports and documents detailing project processes, results, and conclusions; leads or performs additional research as required.
- Support daily report - product summary, chemicals, expected results, operational workup.
- Responsible for conducting technical review of literature, providing feedback and collating all relevant data required for conducting experiments successfully.
- Responsible for setting up R&D equipment for all projects
- Conduct experiments as planned and ensure gathering proper data on custom synthesis, analytical developments, impurity profile etc .
- Overall day to day management of R&D projects activities such as Process development / optimization / Yield improvement / cost reduction / analytical developments/ support to registration activities for various chemicals, Intermediates, formulations and specialty products.
- Vendor development and evaluating commercial aspects with cost effectiveness of the material that is to be procured through purchase.
- Ensuring maintenance of data for implementation and certification for systems like USFDA, GMP, CGMP, GLP, ISO 9001, 14001 and 18001 OSHAS.